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X-linked intellectual disability (previously known as X-linked mental retardation) refers to forms of intellectual disability which are specifically associated with X-linked recessive inheritance. As with most X-linked disorders, males are more heavily affected than females.〔(【引用サイトリンク】title=Fragile X Syndrome - X-linked Mental Retardation and Macroorchidism )〕 Females with one affected X chromosome and one normal X chromosome tend to have milder symptoms. Unlike many other types of intellectual disability, the genetics of these conditions are relatively well understood. It has been estimated there are ~200 genes involved in this syndrome; of these ~100 have been identified. X-linked intellectual disability accounts for ~16% of all cases of intellectual disability in males. ==Syndromes== Several X-linked syndromes include intellectual disability as part of the presentation. These include Coffin-Lowry syndrome, MASA syndrome, X-linked alpha thalassemia mental retardation syndrome, and mental retardation and microcephaly with pontine and cerebellar hypoplasia. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「X-linked intellectual disability」の詳細全文を読む スポンサード リンク
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